Topic: Pseudouridine

The National Science Foundation funded research into "Darwinian Chemical Systems" from 2000 to 2010 to determine if mRNA could write into a host cell's genome. This research led to the formation of Moderna, whose name stands for "Modified RNA." The technology uses pseudouridine to stabilize the mRNA, a process known to be lethal in previous applications.

Dr. Robert Malone discusses the intrinsic toxicity of the cationic lipid RNA complexes used in mRNA vaccines. He references internal Moderna data provided to stockholders showing a 90% adverse event rate in Phase One trials for an influenza vaccine using the same platform. Malone argues that the inflammatory response is a fundamental flaw of the technology that has not been overcome.